2C-B Guide: 2C-B Dosage, Experience, Benefits, & Effects

Some studies even suggest 2C-B may act as an inhibitor of the 5-HT2A receptor 3. Most psychedelics work by activating the 5-HT2A serotonin receptors. This is the primary mechanism of action employed by substances, including LSD, DMT, and psilocybin. Reports from people who took part in our survey that used very high doses (40 mg or higher) or mixed 2C-B with other psychedelics like LSD or psilocybin often mention the experience to be “disorientating” (37%). Users often report feelings of introspection, ego-dissolution, and a stronger sense of empathy and connection with others.

1. Other serotonin receptors may also be involved, such as the 5-HT1A receptors, which could be involved in the emotional changes induced by 2C-B 5.
2. It is currently unknown if there is a fatal dose of 2C-B; higher doses do put users at risk for panic attacks, severe psychosis, delirious states, headaches, and the risk of over-stimulating the heart and circulatory system.
3. Today, most users take 2C drugs to experience the euphoric and psychedelic effects.

Experience

There is limited research on 2C drugs, so it is unproven that there is any real benefit in using this family of drugs as a therapy aid. One study out of Spain in 2015 suggested that people who took 2C-B were more open and less aggressive, but the results were not impressive enough to demonstrate it had real therapeutic effects. Some sources state that 2C-B was used as an aphrodisiac in the 1980s. Today, most users take 2C drugs to experience the euphoric and psychedelic effects.

Other Members of the 2C- Family

It is currently unknown if there is a fatal dose of 2C-B; higher doses do put users at risk for panic attacks, severe psychosis, delirious states, headaches, and the risk of over-stimulating the heart and circulatory system. Because of the drug’s mild anesthetic properties, an injury sustained while under the influence of 2C-B may go unnoticed. A 2017 news report from Ireland stated that 6 young people were hospitalized after consuming 2C-B. Two of the individuals were reportedly injured, covered in blood, and dancing naked, unaware of their injuries. The lack of quality control when liberty bells mushrooms consuming illicit drugs means that there is never a guarantee that any drug is pure. 2C-B is a synthetic psychedelic drug that was first synthesized in 1974 to be used as an aid in therapy.

In this article, we’ll cover everything you need to know about 2C-B — including how it works, what it feels like, and how to use it safely. In Spain, 2C-B was famous fetal alcohol syndrome adults added to Category 2 prohibited substances in 2002. In August 2007, 2C-B, along with many other psychologically active substances,45 was added to Ley 20.000, known as the Ley de Drogas es. Enter your phone number below to receive a free and confidential call from a treatment provider. With respect to the HRS, the highest scores were obtained for intensity, volition and affect subscales (see Figure 2).

The 17 Best Drug Stories We Published in 2023

Subjective effects were recorded at baseline and 2 h after administration, at 6 h subjects were asked to report the maximum effects along 6 h (0–6 h). The Hallucinogenic Rating Scale (HRS) was completed only at 6 h post-administration. When experiencing a bad trip or overdose, seek medical attention immediately. 2C-B is a Schedule I drug with no accepted medical drug use and a high potential for addiction. Possession of 2C-B is punishable by up to 7 years in prison, a fine, or both.

Being in a good state of mind, with trusted friends and a safe environment before taking 2C-B reduces the risk of having a ‘bad’ trip. As another wave of euphoria hits, though, and Mo begins dancing again, those negatives are so far from his mind that they might as well not exist. Nevertheless, the few cases of long-term psychosis attributed to 2C-B are highly questionable, and it’s not known that the drug was even involved. Testing your 2C-B is always good practice even when you trust your supplier. Reagent test kits from Bunk Police can identify hundreds of adulterants and substitutes—offering peace of mind and potentially saving your life. Third Wave’s Ultimate Guide to Sourcing Psychedelic Medicine offers step-by-step instructions for navigating the dark web and recommendations for lesser-known (legal) psychedelic alternatives with similar effects.

Microdosing is the process of taking very small, sub-perceptual doses of a substance. They’re used to increase focus and concentration, improve empathy and connectedness with others, and help achieve a higher level of productivity. 2C-B has also been shown to have aa powerlessness some action at the alpha-adrenergic receptors 3.

Subscribe To Get a Weekly Dose of Psychedelics In Your Inbox

2C-B (4-bromo-2,5-dimethoxyphenethylamine) is a synthetic psychedelic substance derived from mescaline. It was invented in 1974 by a man named Alexander Shulgin — the godfather of MDMA and creator of the entire 2C- family of substances. 2C-B produced robust changes in most subjective effects measured by VAS, ARCI, and VESSPA-SEE. Table 2 shows the results for the different subscales of the questionnaires. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured with an automatic Omron® monitor at baseline and 1, 2, 3, 4, and 6 h after self-administration.

With LSD, the euphoria needs to be earned through experience and mindset. It doesn’t have an inherent euphoric quality to it, so those without the right mindset may not feel any euphoria whatsoever. Most of them were invented around the same time by Alexander Shulgin and documented in one of his books PiHKAL. 2C-B can also be vaporized — but this isn’t a common way of using it, and the long-term health effects of taking 2C-B this way aren’t well understood. Many compounds will change when heated like this, and the byproducts of vaporized 2C-B are not well understood.